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Positive selection of T lymphocytes on fibroblasts

✍ Scribed by Pawlowski, Tomasz; Elliott, Jill D.; Loh, Dennis Y.; Staerz, Uwe D.


Book ID
109784964
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
578 KB
Volume
364
Category
Article
ISSN
0028-0836

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The ligand for positive selection of T l
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T cells are spared from programmed cell death in the thymus after an appropriate interaction between the T-cell receptor and a self peptide/MHC complex; this step is referred to as positive selection. Recent work has focused on precise identification of the positively selecting ligand, and the cell

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