Multidrug resistance (MDR) is a major impediment to successful chemotherapy for lung cancer. Overexpression of multidrug resistance-associated protein 1 (MRP1) appears to be involved in MDR development in lung cancer cells. A number of chemotherapeutic agents including doxorubicin (DOX) were reporte
β¦ LIBER β¦
Positive Selection in the N-Terminal Extramembrane Domain of Lung Surfactant Protein C (SP-C) in Marine Mammals
β Scribed by Natalie J. Foot; Sandra Orgeig; Stephen Donnellan; Terry Bertozzi; Christopher B. Daniels
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 242 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-2844
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## Abstract The stability of the Nβterminal domain of the ribosomal protein L9, NTL9, from __Baccilus stearothermophilus__ has been monitored by circular dichroism at various temperatures and chemical denaturant concentrations in H~2~O and D~2~O. The basic thermodynamic parameters for the unfolding