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Positive Selection and Rates of Evolution in Immunodeficiency Viruses from Humans and Chimpanzees

โœ Scribed by David P. Mindell

Book ID
123639716
Publisher
National Academy of Sciences
Year
1996
Tongue
English
Weight
993 KB
Volume
93
Category
Article
ISSN
0027-8424

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Population genetic and virological methods yield estimates for the mean replication rate of the Human Immunodeficiency Virus type 1 (HIV-1) that differ by six fold. I present a simple model that can reconcile the estimates obtained from each method by considering the role of intra-host population st