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Positive inotropic action of blood plasma on rabbit heart papillary muscle

โœ Scribed by E. G. Vornovitskii; N. A. Len'kova; L. A. Vasilets; B. I. Khodorov


Publisher
Springer US
Year
1982
Tongue
English
Weight
366 KB
Volume
94
Category
Article
ISSN
0007-4888

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Actions of dolasetron and its major meta
โœ Robert Dumaine; Hali A. Hartmann; Derek J. Leishman; Arthur M. Brown; Martin Gal ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 695 KB

The present study evaluated the effects of the anti-emetic 5-HT3 antagonist dolasetron and its major metabolite MDL 73,405 on guinea-pig papillary muscle fibres and human heart sodium channels expressed in Xenopus oocytes. Dolasetron and MDL 73,405 (3-10 p M ) reduced the maximum depolarization rate