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Positive gallium scan in the syndrome of opsoclonus—myoclonus treated with adrenocorticotropic hormone

✍ Scribed by Maria Gumbinas; Edward S. Gratz; Gerald S. Johnston; Allen D. Schwartz

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 191 KB
Volume: 54
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19840901)54:5<815::aid-cncr2820540509>3.0.co;2-#

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✦ Synopsis

The syndrome of opsoclonus and myoclonus may be the first presenting symptom of neuroblastoma. The disorder is often controlled by treatment with adrenocorticotropic hormone (ACTH). A child with this disorder and treated with ACTH gel had abnormal uptake of 67Ga in both adrenal glands during studies to attempt to detect an occult neuroblastoma. Repeat 67Ga scans proved to be normal once the ACTH was discontinued and the patient was treated with prednisone. It is concluded that ACTH stimulation of normal adrenal tissue was responsible for these abnormal findings.

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