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Positive feedback in cellular control systems

โœ Scribed by Alexander Y. Mitrophanov; Eduardo A. Groisman

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
412 KB
Volume
30
Category
Article
ISSN
0265-9247

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โœฆ Synopsis

Abstract

Feedback loops have been identified in a variety of regulatory systems and organisms. While feedback loops of the same type (negative or positive) tend to have properties in common, they can play distinctively diverse roles in different regulatory systems, where they can affect virulence in a pathogenic bacterium, maturation patterns of vertebrate oocytes and transitions through cell cycle phases in eukaryotic cells. This review focuses on the properties and functions of positive feedback in biological systems, including bistability, hysteresis and activation surges. BioEssays 30:542โ€“555, 2008. ยฉ 2008 Wiley Periodicals, Inc.

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