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Positional Cloning of a Novel Fanconi Anemia Gene, FANCD2

✍ Scribed by Cynthia Timmers; Toshiyasu Taniguchi; James Hejna; Carol Reifsteck; Lora Lucas; Donald Bruun; Matthew Thayer; Barbara Cox; Susan Olson; Alan D. D'Andrea; Robb Moses; Markus Grompe


Book ID
117736468
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
642 KB
Volume
7
Category
Article
ISSN
1097-2765

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## Ponder Fanconi anemia (FA) is an autosomal recessive disorder associated with hypersensitivity to DNA cross-linking agents and bone marrow failure. At least four complementation groups have been defined, and the FA group C gene (FAC) has been cloned. We have screened 76 unrelated FA patients of