Portacaval shunting attenuates portal hypertension and systemic hypotension in rat anaphylactic shock

Nω-Nitro-L-arginine Administration Corre

Nω-Nitro-L-arginine Administration Corrects Peripheral Vasodilation and Systemic Capillary Hypotension and Ameliorates Plasma Volume Expansion and Sodium Retention in Portal Hypertensive Rats

✍ Fa-Yauh Lee; Luis A. Colombato; Agustin Albillos; Roberto J. Groszmann 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 830 KB

In portal hypertensive states, peripheral vasodilation leads to sodium retention and plasma volume expansion. N"-nitro-L-arginine, a specific biosynthesis inhibitor of the vasodilator nitric oxide, has been shown to acutely reverse peripheral vasodilation and the vascular hyporesponsiveness to endog