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Porphyromonas gingivalisModulates the Production of Interleukin 8 and Monocyte Chemotactic Protein 1 in Human Vascular Endothelial Cells

✍ Scribed by Michiyo Kobayashi-Sakamoto; Emiko Isogai; Kimiharu Hirose


Publisher
Springer
Year
2003
Tongue
English
Weight
409 KB
Volume
46
Category
Article
ISSN
0343-8651

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## Abstract Blood vessel injury results in limited oxygen tension and diffusion leading to hypoxia, increased anaerobic metabolism, and elevated production of acidic metabolites that cannot be easily removed due to the reduced blood flow. Therefore, an acidic extracellular pH occurs in the local mi