Porphyrin synthesis by the “3 + 1” methodology: A superior approach for the preparation of porphyrins with fused 9,10-phenanthroline subunits

Porphyrins with exocyclic rings. Part 9

Porphyrins with exocyclic rings. Part 9 [1] Synthesis of porphyrins by the ‘3 + 1’ approach

✍ Timothy D. Lash 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 292 KB 👁 1 views

Tripyrrane dibenzyl esters are readily available from the reaction of two equivalents of 5-acetoxymethylpyrrole-2-carboxylates with 2,5-diunsubstituted pyrroles in refluxing acetic acid-ethanol. Hydrogenolysis of the benzyl ester moieties affords the corresponding dicarboxylic acids, and subsequent