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Porphyrin Formation in Actinic Keratosis and Basal Cell Carcinoma after Topical Application of Methyl 5-Aminolevulinate

✍ Scribed by Angell-Petersen, Even; Sørensen, Roar; Warloe, Trond; Soler, Ana Maria; Moan, Johan; Peng, Qian; Giercksky, Karl-Erik


Book ID
110049131
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
239 KB
Volume
126
Category
Article
ISSN
0022-202X

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The bioconversion of 5-aminolevulinic acid (ALA) into hydrophobic protoporphyrin IX and other water-soluble porphyrins was investigated in Ehrlich ascite carcinoma (EAC) cells and in a myeloma cell line. The effects of irradiation (514 nm), temperature, incubation time and added glucose on the relat