We studied the prevalence of hepatitis C virus (HCV) infection in 20 Japanese patients with sporadic-type porphyria cutanea tarda (PCT). Seventeen of the 20 patients (85%) had anti-HCV antibodies. Biochemical remission was observed in nine patients, six of whom still had positive HCV RNA copies. The
Porphyria cutanea tarda and porphyria variegata unmasked by viral hepatitis
β Scribed by P.R. COBURN; J.C. COLEMAN; J.J. CREAM; J.L.M. HAWK; S.G.S. LAMB; I.M. MURRAY-LYON
- Book ID
- 108690582
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 262 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0307-6938
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In some, but not all countries, porphyria cutanea tarda (PCT) has been associated with chronic infection with the hepatitis C virus (HCV). Recently, PCT has also been associated with mutations in the HFE gene that are associated with HLA-linked hereditary hemochromatosis. Until now, few studies of t
Porphyria cutanea tarda in human beings is believed to be due to reduced hepatic uroporphyrinogen decarboxylase activity. However, extrinsic factors such as alcohol abuse and drug intake are required for clinical manifestation of the disease. In addition to typical cutaneous lesions, patients with p
From 1995 to 1997, we prospectively evaluated the prevalence of hepatitis C virus (HCV) RNA in 124 patients with porphyria cutanea tarda (PCT) from Northern France (83 sporadic and 41 familial PCT). Serum samples were analyzed for ferritin, transaminases, HCV antibodies, and HCV RNA. In addition, ge