Porous Silicon for Biomedical Applications

✍ Scribed by H.A. Santos (Eds.)

• Publisher: Woodhead Publishing
• Year: 2014
• Tongue: English
• Leaves: 551
• Series: Woodhead Publishing Series in Biomaterials
• Edition: 1
• Category: Library

✦ Synopsis

Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous Silicon for Biomedical Applications provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial.

Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing, and explores the optical properties of porous silicon materials; in vivo imaging assessment and radiolabelling of porous silicon; and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumor targeting and imaging, and porous silicon scaffolds for functional tissue engineering, stem cell growth, and osteodifferentiation.

With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in the field.

• Comprehensive review of porous silicon focusing on the fabrication and properties of this emerging material
• Specifically discusses drug delivery and orthopedic applications of porous silicon
• Aimed at materials researchers and scientists in the biomaterials industry - particularly those concerned with drug delivery and orthopedics

✦ Table of Contents

Content:
Front matter, Pages i-iii
Copyright, Page iv
Contributor contact details, Pages xiii-xvi, H.A. Santos, L.T. Canham, J. Salonen, E. Mäkilä, N. Koshida, K.W. Kolasinski, J.J. Gooding, Y. Zhu, L. De Stefano, I. Rea, P. Giardina, S. Longobardi, V. Torres-Costa, R.J. Martín-Palma, S. Srinivasan, F. Leonard, T.M. Kuncewicz, B. Godin, A.J. Airaksinen, Q. Liu, V.L. Brown, et al.
Woodhead Publishing Series in Biomaterials, Pages xvii-xxi
Foreword, Pages xxiii-xxiv, Mauro Ferrari, Leigh Canham
Preface, Pages xxv-xxix, Hélder A. Santos
Dedication, Page xxxi
1 - Porous silicon for medical use: from conception to clinical use, Pages 3-20, L.T. Canham
2 - Thermal stabilization of porous silicon for biomedical applications, Pages 21-34, J. Salonen, E. Mäkilä
3 - Thermal properties of nanoporous silicon materials, Pages 35-51, N. Koshida
4 - Photochemical and nonthermal chemical modification of porous silicon for biomedical applications, Pages 52-80, K.W. Kolasinski
5 - Modifying porous silicon with self-assembled monolayers for biomedical applications, Pages 81-103, J.J. Gooding, Y. Zhu
6 - Protein-modified porous silicon films for biomedical applications, Pages 104-128, I. Rea, P. Giardina, S. Longobardi, L. De Stefano
7 - Biocompatibility of porous silicon for biomedical applications, Pages 129-181, D. Liu, M.-A. Shahbazi, L.M. Bimbo, J. Hirvonen, H.A. Santos
8 - Optical properties of porous silicon materials for biomedical applications, Pages 185-222, V. Torres-Costa, R.J. Martín-Palma
9 - In vivo imaging assessment of porous silicon, Pages 223-240,241e-252e,241-252, S. Srinivasan, F. Leonard, T.M. Kuncewicz, B. Godin
10 - Radiolabeled porous silicon for bioimaging applications, Pages 253-269, A.J. Airaksinen
11 - Desorption/ionization on porous silicon (DIOS) for metabolite imaging, Pages 270-285, Q. Liu, V.L. Brown, L. He
12 - Porous silicon for bacteria detection, Pages 286-303, N. Massad-Ivanir, E. Segal
13 - Nanoporous silicon biosensors for DNA sensing, Pages 304-333, G.A. Rodriguez, J.L. Lawrie, S.M. Weiss
14 - Drug loading and characterization of porous silicon materials, Pages 337-355, V.-P. Lehto, J. Riikonen
15 - Nanoporous silicon to enhance drug solubility, Pages 356-373, C.A. Prestidge, T.J. Barnes
16 - Multistage porous silicon for cancer therapy, Pages 374-402, J.S. Fernandez-Moure, M. Evangelopoulos, S. Scaria, J.O. Martinez, B.S. Brown, A.C. Coronel, P. Chan, B. Weiner, M. Ferrari, E. Tasciotti
17 - Porous silicon for tumour targeting and imaging, Pages 403-419, J-H. Park
18 - Porous silicon–polymer composites for cell culture and tissue engineering applications, Pages 420-469, S.J.P. McInnes, N.H. Voelcker
19 - Porous silicon and related composites as functional tissue engineering scaffolds, Pages 470-485, J.L. Coffer
20 - Porous silicon scaffolds for stem cells growth and osteodifferentiation, Pages 486-506, P.-Y. Collart Dutilleul, D. Deville De Périère, F.J. Cuisinier, F. Cunin, C. Gergely
Index, Pages 507-526