Porous polyurethane vascular prostheses with variable compliances
✍ Scribed by Liu, Shu Qin ;Kodama, Makoto
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 877 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
A new technique for the preparation of porous vascular prostheses was investigated. Polyurethane solution (5 to 15 wt%) was injected into a mold. After freezing at low temperature (OOC -196"C), solvents were dissolved out with water at 0°C to form porous tubes. The average pore size (several microns to 70 pm), pore occupation (10% to 51%), and compliance (3% to 35%) were easily changed by changing polyurethane concentration, freezing temperature, and freezing methods. Compliances could be decreased gradually by heat treatment. This technique can give a proper pore size (30-60 pm) for tissue ingrowth, and a suitable compliance for matching with arteries and veins. This method might give a desired compliant graft for artificial implantation with the presently valid medical polymers.