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Porcine pancreatic lipase mediated selective acylation of primary alcohols in organic solvents

✍ Scribed by Sowmianarayanan Ramaswamy; Brian Morgan; Allan.C. Oehlschlager

Publisher: Elsevier Science
Year: 1990
Tongue: French
Weight: 209 KB
Volume: 31
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)97408-2

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✦ Synopsis

Porcine pancreatic lipase mediated acylation of l,n-diols and triols affords primary acytated products in high yields.

The regio-and stereospecificity of enzyme catalyzed reactions are the envy of synthetic chemists.1

The use of enzymes in organic synthesis has become increasingly popular since it was realized that many enzymes can function in organic sofvents without lo88 of specificity.8

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