✦ LIBER ✦
PorA VR3 Typing Database: A web-based resource for the determination of PorA VR3 alleles of Neisseria meningitidis
✍ Scribed by Ivano de Filippis; Vivek Gopalan; Yentram Huyen
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 75 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1567-1348
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✦ Synopsis
The variable regions (VR) of the surface-exposed PorA protein of Meningococci are used for subtyping and are considered the most abundant epitopes of outer membrane vesicle-based vaccine preparations. We have developed both a database that maintains all the known VR3 alleles and a web-based application for the rapid identification and submission of new VR3 variants based on sequence comparison.