Population Stratification in Epidemiologic Studies of Common Genetic Variants and Cancer: Quantification of Bias
β Scribed by Wacholder, S.
- Book ID
- 121796362
- Publisher
- Oxford University Press
- Year
- 2000
- Tongue
- English
- Weight
- 150 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0027-8874
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Systematic errors, or bias, can arise at several stages of a study, including selection of subjects, measurement of exposure and disease, and data analysis. Little attention appears to have been paid to potential sources of bias in genetic epidemiologic studies, despite the fact that the study of un
## Abstract The potential for bias from population stratification (PS) has raised concerns about caseβcontrol studies involving admixed ethnicities. We evaluated the potential bias due to PS in relating a binary outcome with a candidate gene under simulated settings where study populations consist