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Population pharmacokinetic modelling to assess clinical drug-drug interaction between AZD7325 and midazolam

โœ Scribed by Zhou, D.; Lu, Z.; Sunzel, M.; Xu, H.; Al-Huniti, N.


Book ID
121746135
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
624 KB
Volume
39
Category
Article
ISSN
0269-4727

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โœ Toyohiro Sawada; Kazuhiro Sako; Keiichi Yoshihara; Katsutoshi Nakamura; Shigehar ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 107 KB

The purpose of this study was to investigate whether the use of a timed-release (TR) drug formulation can avoid unfavorable pharmacokinetic drug-drug interactions in vivo. First, the effects of the time interval between administration of midazolam and diltiazem on the known drug-drug interaction bet