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Population Pharmacokinetic Model of Human Insulin Following Different Routes of Administration

✍ Scribed by Potocka, Elizabeth; Baughman, Robert A.; Derendorf, Hartmut


Book ID
126706817
Publisher
Sage Publications
Year
2011
Tongue
English
Weight
410 KB
Volume
51
Category
Article
ISSN
0091-2700

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Studies were conducted to examine the absorption and disposition kinetics of insulin in dogs following intravenous (IV) and subcutaneous (SC) administration of commercial preparations. After IV and SC dosing, the plasma levels were described by models which considered basal insulin level contributio