𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Population choice in mapping genes for complex diseases

✍ Scribed by Wright, Alan F; Carothers, Andrew D; Pirastu, Mario


Book ID
109827132
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
141 KB
Volume
23
Category
Article
ISSN
1061-4036

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Multipoint linkage disequilibrium mappin
✍ Kung-Yee Liang; Fang-Chi Hsu; Terri H. Beaty πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 107 KB

## Abstract Linkage disequilibrium (LD) or association studies using case‐parent trios have become a common approach to locate unobserved susceptibility genes underlying complex diseases. With the availability of ever more dense marker maps, how to utilize the information carried by multiple marker

Mapping multiple genes for quantitative
✍ Hsiu-Khuern Tang; David Siegmund πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 95 KB

## Abstract Models for complex and quantitative traits that involve multiple, possibly interacting, genes are described. Methods of linkage analysis are developed that utilize special features of these models, and their power is compared with that of simple genome scans that ignore these special fe

Using endophenotypes for pathway cluster
✍ Wen-Harn Pan; Ke-Shiuan Lynn; Chun-Houh Chen; Yi-Lin Wu; Chung-Yen Lin; Hsing-Yi πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 369 KB

## Abstract Nature determines the complexity of disease etiology and the likelihood of revealing disease genes. While culprit genes for many monogenic diseases have been successfully unraveled, efforts to map major complex disease genes have not been as productive as hoped. The conceptual framework