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Pooling for Improved Screening of Combinatorial Libraries for Directed Evolution

โœ Scribed by Karen M. Polizzi; Monal Parikh; Cody U. Spencer; Ichiro Matsumura; Jay H. Lee; Matthew J. Realff; Andreas S. Bommarius

Book ID
109387433
Publisher
American Institute of Chemical Engineers
Year
2006
Tongue
English
Weight
238 KB
Volume
22
Category
Article
ISSN
8756-7938

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A new method for the screening of solid-
A new method for the screening of solid-phase combinatorial libraries for affinity chromatography
โœ A. Cecรญlia A. Roque; M. ร‚ngela Taipa; Christopher R. Lowe ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 214 KB ๐Ÿ‘ 1 views

## Abstract A new methodology for the rapid assessment of affinity ligands synthesized by combinatorial solidโ€phase chemistry is reported. This screening strategy utilizes the target protein conjugated to FITC, and represents an almost universal technique for the preliminary screening of solidโ€phas