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PON1 55and192Gene Polymorphisms in Type 2 Diabetes Mellitus Patients in a Turkish Population

✍ Scribed by Mehmet Ali Ergun; Erkan Yurtcu; Huseyin Demirci; Mustafa N. Ilhan; Vahit Barkar; Ilhan Yetkin; Adnan Menevse

Publisher
Springer
Year
2010
Tongue
English
Weight
176 KB
Volume
49
Category
Article
ISSN
0006-2928

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## Abstract Paraoxonase 1 (PON 1) is a high‐density lipoprotein (HDL)‐associated enzyme with antioxidant function protecting low‐density lipoprotein (LDL) from oxidation. PON 1 has two amino acid polymorphisms in coding region; L/M 55 and Q/R 192. These polymorphisms modulate paraoxonase activity o