Indomethacin release behaviors from pH a
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Heung Soo Shin; So Yeon Kim; Young Moo Lee
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Article
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1997
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John Wiley and Sons
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English
⚖ 223 KB
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A temperature-and pH-responsive drug delivery system was studied by using interpenetrating polymer network (IPN) hydrogels constructed with poly(acrylic acid) (PAAc) and poly(vinyl alcohol) (PVA). The release of indomethacin incorporated into these hydrogels showed pulsatile patterns in response to