𝔖 Bobbio Scriptorium
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Polyvinyl alcohol-immobilized whole-cell preparations for the biotransformation of nitriles

✍ Scribed by Andrea Bauer; Norman Layh; Christoph Syldatk; Andrew Willetts

Publisher
Springer Netherlands
Year
1996
Tongue
English
Weight
388 KB
Volume
18
Category
Article
ISSN
0141-5492

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✦ Synopsis

Resting cells of Rhodococcus sp. ATCC 39484 were immobilized in polyvinyl alcohol (PVA). The PVA-beads showed nitrile-hydrolysing activity with propionitrile as a model substrate. Drying of the beads resulted in a loss of weight of 85 %. Re-swollen beads showed no loss in activity. In a continuously-operated fixed-bed bioreactor, beads were able to convert substrate concentrations up to 100 mM.

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