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Polytopic Oxazoline-Based Chiral Ligands for Cyclopropanation Reactions: A New Strategy to Prepare Highly Recyclable Catalysts

✍ Scribed by José I. García; Clara I. Herrerías; Beatriz López-Sánchez; José A. Mayoral; Oliver Reiser


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
407 KB
Volume
353
Category
Article
ISSN
1615-4150

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✦ Synopsis


Abstract

New polytopic chiral copper complexes based on azabis(oxazoline) moieties have been synthesized and applied in cyclopropanation reactions of several alkenes. Excellent enantioselectivities have been obtained in all cases and additionally, the catalysts have been recovered in up to 14 cycles without noticeable loss of activity and selectivity. Analysis of the copper complexes by mass spectrometry suggests the formation of coordination polymers, representing the resting state of the catalysts.