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Polystyrene-supported selenosulfonates: efficient reagents for the synthesis of acetylenic sulfones

✍ Scribed by Hao Qian; Xian Huang


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
94 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


Two novel polystyrene-supported selenosulfonate reagents have been developed for AIBN-catalyzed addition to acetylenes and have been used for the synthesis of acetylenic sulfones.


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A novel reagent (diisopropoxyphosphorylmethanesulfonylmethanesulfonylmethyl)-phosphonic acid diisopropyl ester (8) capable of forming symmetrical and non-symmetrical a,b unsaturated gem-disulfones is reported. Both aromatic and aliphatic aldehydes react in good yields to give exclusively the trans i