Polysomnography in preterm infants and children with chronic lung disease

✍ Scribed by Sharon A. McGrath-Morrow; Timothy Ryan; Brian M. McGinley; Sande O. Okelo; Laura M. Sterni; J. Michael Collaco

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 88 KB
• Volume: 47
• Category: Article
• ISSN: 8755-6863
• DOI: 10.1002/ppul.21522

✦ Synopsis

Objective:

To determine the utility of overnight polysomnography (psg) in assessing pulmonary reserve in stable preterm children with chronic lung disease (cld).

Study design:

A retrospective review and descriptive study of overnight psgs and clinic visits of preterm infants/children less than 3 years of age who were diagnosed with bronchopulmonary dysplasia at discharge from the hospital and enrolled in the johns hopkins cld patient registry between 2008 and 2010.

Results:

Sixty-two clinically stable patients underwent at least one overnight polysomnogram for clinical indications. the majority of patients were referred for oxygen titration (71%). psgs from first studies revealed a mean respiratory disturbance index (rdi) of 8.2 ± 10.1 events/hr and a mean o(2) saturation (sao(2) ) nadir of 86.2 ± 5.7%. in patients who underwent more than one psg (n = 23), a significant decrease in rdi (p < 0.001) was found between the first study (mean age: 8.0 ± 3.3 months) and second study (mean age: 13.4 ± 5.2 months). outpatient clinical measures of mean room air sao(2) and respiratory rate were not predictive of psg measures of rdi and sao(2) nadir.

Conclusion:

Mean rdi was higher in stable preterm infants/children with cld compared to previously published controls. rdi decreased with age in stable preterm infants/children with cld suggesting improved pulmonary reserve with age. outpatient clinical measures (respiratory rate and room air sao(2) ) did not correlate with rdi and sao(2) nadir indicating that overnight psg is more sensitive in assessing pulmonary reserve than outpatient clinical measures.