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Polyreactive antigen-binding B cells are the predominant cell type in the newborn B cell repertoire

✍ Scribed by Zhi Jian Chen; C. James Wheeler; Wei Shi; Ava J. Wu; Cheryl H. Yarboro; Michael Gallagher; Abner Louis Notkins

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
155 KB
Volume
28
Category
Article
ISSN
0014-2980

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✍ Marinette Moynier; Mohamed Abderrazik; Catherine Didry; Jacques Sany; Jean Broch πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 571 KB

Objective. We sought to compare the frequencies of precursors producing IgM rheumatoid factors (IgM-RFs) in synovial fluid and peripheral blood B cells from patients with rheumatoid arthritis (RA). Methods. We used limiting-dilution analysis of Epstein-Barr virus-activated B cells from seropositive