Polyoma virus and simian virus 40 as cancer models: History and perspectives
β Scribed by Sarah J.L. Atkin; Beverly E. Griffin; Stephen M. Dilworth
- Book ID
- 113900414
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 300 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1044-579X
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## Abstract The hostβvirus interactions of Simian virus 40 (SV^40^) and polyoma virus (Py) with cell lines established from a teratocarcinoma were studied. The cells utilized in this study were the multipotential stem cell of the teratocarcinoma, embryonal carcinoma, and differentiated cells derive
## Abstract Cultures of the multipotential stem cell, embryonal carcinoma (EC), of a murine teratocarcinoma were treated with 5βbromodeoxyuridine (BrdU). Within 2β4 days at concentrations of 1β50 mΜgm/ml of BrdU, there was a marked change in the morphology of cells observed by light and electron mi