Polymyalgia Rheumatica in an American Indian

✍ Scribed by Robert C. Jacobs

• Publisher: John Wiley and Sons
• Year: 1977
• Tongue: English
• Weight: 105 KB
• Volume: 20
• Category: Article
• ISSN: 0004-3591
• DOI: 10.1002/art.1780200724

✦ Synopsis

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have evidence of either sacroiliitis or spondylitis. On the other hand, African and American blacks have a very low incidence of AS. As might be anticipated, recent surveys now disclose that the prevalence of the HLA-B27 is higher in North American Indians and lower in blacks than in Caucasian whites (4).

It might be reasonable to speculate that the pathogenesis of AS evolves in the following manner. Variable inciting factors, such as ulcerative colitis and other associated disorders as well as urogenital infection or even trauma, might precipitate the evolution of spondylitis in a genetically predisposed individual having the B27 marker. The disease may then be perpetuated by some form of immune mechanism currently unidentified.