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Polymorphisms ofUGT1A9andUGT2B7influence the pharmacokinetics of mycophenolic acid after a single oral dose in healthy Chinese volunteers

✍ Scribed by Dong Guo, Liang-Fang Pang, Yang Han, Hong Yang…


Book ID
120759365
Publisher
Springer
Year
2012
Tongue
English
Weight
263 KB
Volume
69
Category
Article
ISSN
0031-6970

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The pharmacokinetics of valproic acid (VPA) was investigated in six healthy volunteers. This was done by monitoring total and free (unbound) valproic acid levels in the serum, and the amount of one of its metabolites, VPA glucuronide, in the urine as a function of time, after a single dose administr