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Polymorphisms of theXRCC1,XRCC3, &XPDgenes, and colorectal cancer risk: a case-control study in Taiwan

✍ Scribed by Chih-Ching Yeh; Fung-Chang Sung; Reiping Tang; Chung Rong Chang-Chieh; Ling-Ling Hsieh


Book ID
115010639
Publisher
BioMed Central
Year
2005
Tongue
English
Weight
292 KB
Volume
5
Category
Article
ISSN
1471-2407

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XRCC2 and XRCC3 proteins are structurally and functionally related to RAD51 which play an important role in the homologous recombination, the process frequently involved in cancer transformation. In our previous work we show that the 135G>C polymorphism (rs1801320) of the __RAD51__ gene can modify t