## Abstract The multifunctional cytokine interleukin‐6 (IL‐6) is involved in inflammatory processes in the central nervous system and increased levels of IL‐6 have been found in patients with Parkinson's disease (PD). It is known that estrogen inhibits the production of IL‐6, via action on estrogen
✦ LIBER ✦
Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer's disease
✍ Scribed by Metin Bagli; Andreas Papassotiropoulos; Harald Hampel; Karin Becker; Frank Jessen; Katharina Bürger; U. Ptok; Marie Luise Rao; Hans-Jürgen Möller; Wolfgang Maier; Reinhard Heun
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 359 KB
- Volume
- 253
- Category
- Article
- ISSN
- 1433-8491
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## 817 ated with increased risk for AD, at least in the Korean population. Nevertheless, it cannot be excluded that the association between IL-1A (-889) C/T polymorphism and AD observed in previous studies might be the result of linkage disequilibrium with a yet unidentified gene on chromosome 2.