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Polymorphisms in theIGF-1andIGFBP3promoter and the risk of breast cancer

✍ Scribed by Kerstin Wagner; Kari Hemminki; Elisabeth Israelsson; Ewa Grzybowska; Magnus Söderberg; Jolanta Pamula; Wioletta Pekala; Helena Zientek; Danuta Mielzynska; Ewa Siwinska; Asta Försti


Publisher
Springer US
Year
2005
Tongue
English
Weight
228 KB
Volume
92
Category
Article
ISSN
0167-6806

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✍ Sandrine Tchatchou; Angela Riedel; Stefan Lyer; Julia Schmutzhard; Olga Strobel- 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB 👁 1 views

According to present estimations, the unfavorable combination of alleles with low penetrance but high prevalence in the population might account for the major part of hereditary breast cancer risk. Deleted in Malignant Brain Tumors 1 (DMBT1) has been proposed as a tumor suppressor for breast cancer