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Polymorphisms in the SUFU gene are associated with organ injury protection and sepsis severity in patients with Enterobacteriacea Bacteremia

✍ Scribed by Henao-Martínez, Andrés F.; Agler, Anne Hermetet; LaFlamme, Daniel; Schwartz, David A.; Yang, Ivana V.

Book ID
123173374
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
411 KB
Volume
16
Category
Article
ISSN
1567-1348

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## Abstract ## Background Toll-like receptor (TLR) 9 is the pattern recognition receptor for microbial DNA. Genetic variation within pattern recognition receptors for bacterial endotoxin and exotoxin has been shown to be associated with the risk of sepsis and organ dysfunction in critical illness.