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Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma

✍ Scribed by Gao, Li; Grant, Audrey V.; Rafaels, Nicholas; Stockton-Porter, Maria; Watkins, Tonya; Gao, Peisong; Chi, Peter; Muñoz, Melba; Watson, Harold; Dunston, Georgia; Togias, Alkis; Hansel, Nadia; Sevransky, Jonathan; Maloney, James P.; Moss, Marc; Shanholtz, Carl; Brower, Roy; Garcia, Joe G.N.; Grigoryev, Dmitry N.; Cheadle, Christopher; Beaty, Terri H.; Mathias, Rasika A.; Barnes, Kathleen C.


Book ID
119279190
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
534 KB
Volume
119
Category
Article
ISSN
1097-6825

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## Abstract Asthma is a complex phenotype influenced by environmental and genetic factors for which severe irreversible structural airway alterations are more frequently observed in African Americans. In addition to a multitude of factors contributing to its pathobiology, increased amounts of myosi