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Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced

✍ Scribed by Galicia, J C; Tai, H; Komatsu, Y; Shimada, Y; Akazawa, K; Yoshie, H


Book ID
110037633
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
95 KB
Volume
5
Category
Article
ISSN
1466-4879

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The human interleukin-6 receptor (IL6R) is responsible for signal transduction of IL6 that might have associations with immune diseases and various infectious diseases. We have sequenced all 10 exons including the putative splicing site to identify single nucleotide polymorphisms in IL6R. Seven nove