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Polymorphisms in the DNA Repair Enzyme XPD are Associated with Increased Levels of PAH–DNA Adducts in a Case-Control Study of Breast Cancer

✍ Scribed by Deliang Tang; Stan Cho; Andrew Rundle; Senqing Chen; David Phillips; Jingzhi Zhou; Yanzhi Hsu; Freya Schnabel; Alison Estabrook; Frederica P. Perera


Book ID
110390330
Publisher
Springer US
Year
2002
Tongue
English
Weight
86 KB
Volume
75
Category
Article
ISSN
0167-6806

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## Abstract Interleukin 1β (IL‐1β) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (T‐31C and C‐511T) in the __IL‐1__β gene promote