Polymorphisms in the coding region of X-ray repair complementing group 4 and aflatoxin B1-related hepatocellular carcinoma
✍ Scribed by Long, Xi-Dai; Yao, Jin-Guang; Zeng, Zhi; Ma, Yun; Huang, Xiao-Ying; Wei, Zhong-Hua; Liu, Min; Zhang, Jian-Jun; Xue, Feng; Zhai, Bo; Xia, Qiang
- Book ID
- 125484705
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 767 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0270-9139
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Genetic polymorphisms in DNA repair genes may influence individual variations in DNA repair capacity, and this may be associated with the risk and outcome of hepatocellular carcinoma (HCC) related to aflatoxin B1 (AFB1) exposure. In this study, we focused on the polymorphism of xeroderma pigmentosum
## Abstract ## BACKGROUND. X‐ray repair cross complementing group 1 (XRCC1) is important in the repair of single‐strand DNA breaks caused by endogenous oxidative species and exogenous carcinogens. ## METHODS. This tertiary cancer center‐based, case‐control association study included 138 patients