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Polymorphisms in methionine synthase reductase and betaine-homocysteine S-methyltransferase genes: Risk of placental abruption

โœ Scribed by Cande V. Ananth; Denise A. Elsasser; Wendy L. Kinzler; Morgan R. Peltier; Darios Getahun; Daniel Leclerc; Rima R. Rozen


Book ID
116987973
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
149 KB
Volume
91
Category
Article
ISSN
1096-7192

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Folic acid administration to women in the periconceptional period reduces the occurrence of neural tube defects (NTDs) in their offspring. A polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), 677CยจT, is the first genetic risk factor for NTDs in man identified at the molec