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Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people

✍ Scribed by Christie Cluett; Carol Brayne; Robert Clarke; Grimley Evans; Fiona Matthews; David C. Rubinsztein; Felicia Huppert; David J. Llewellyn; Neil Rice; William Henley; Timothy M. Frayling; Anna Murray; David Melzer


Book ID
116781399
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
133 KB
Volume
31
Category
Article
ISSN
0197-4580

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✍ Brenda Yan Fu; Suk Ling Ma; Nelson Leung Sang Tang; Cindy Woon Chi Tam; Victor W πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 74 KB

## Abstract ## Objectives We previously found that the polymorphisms of cholesterol 24‐hydroxylase (CYP46A1) gene were associated with the risk of Alzheimer's disease (AD) in Chinese. However, its effect in predicting progression of cognitive decline remains unknown. ## Methods Two hundred and e