## Abstract We investigated whether variants in sex steroid hormone metabolism genes modify the effect of hormone therapy (HT) on endometrial cancer risk in postmenopausal nonβHispanic white women. A nested caseβcontrol study was conducted within the California Teachers Study (CTS). We genotyped ht
Polymorphisms in Genes Involved in Sex Hormone Metabolism, Estrogen Plus Progestin Hormone Therapy Use, and Risk of Postmenopausal Breast Cancer
β Scribed by Diergaarde, B.; Potter, J. D.; Jupe, E. R.; Manjeshwar, S.; Shimasaki, C. D.; Pugh, T. W.; DeFreese, D. C.; Gramling, B. A.; Evans, I.; White, E.
- Book ID
- 126043366
- Publisher
- American Association for Cancer Research
- Year
- 2008
- Tongue
- English
- Weight
- 191 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1055-9965
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## Abstract Menopausal hormone therapy (HT) is associated with increased breast cancer risk among postmenopausal women. Nuclear receptors are involved in steroid hormoneβ and xenobioticβmediated signal transduction playing a crucial role in regulating gene expression. Therefore, variations within t
## Abstract We assessed the relationship between serum concentrations of estrogens, androgens, and sex hormoneβbinding globulin and risk of breast cancer among postmenopausal women. Study participants provided serum prior to breast biopsy or mastectomy in 3 hospitals in Grand Rapids, Michigan betwe