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Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes

✍ Scribed by Kalnina, Ineta; Zaharenko, Linda; Vaivade, Iveta; Rovite, Vita; Nikitina-Zake, Liene; Peculis, Raitis; Fridmanis, Davids; Geldnere, Kristine; Jacobsson, Josefin A.; Almen, Markus S.; Pirags, Valdis; Schiöth, Helgi B.; Klovins, Janis


Book ID
121470306
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
372 KB
Volume
527
Category
Article
ISSN
0378-1119

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## Homogeneity of the age at diagnosis of Type 2 diabetes was studied in 1,228 sibs in 300 unrelated families: 100 consecutive singleaffected and 200 consecutive multipleaffected ones. There were 635 diabetic sibs. The mean and median age at diagnosis in all affected individuals was 50 years (range