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Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and meta-analyses

✍ Scribed by Montserrat García-Closas; Kathleen M. Egan; Polly A. Newcomb; Louise A. Brinton; Linda Titus-Ernstoff; Stephen Chanock; Robert Welch; Jolanta Lissowska; Beata Peplonska; Neonila Szeszenia-Dabrowska; Witold Zatonski; Alicja Bardin-Mikolajczak; Jeffery P. Struewing

Publisher: Springer
Year: 2006
Tongue: English
Weight: 281 KB
Volume: 119
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-006-0135-z

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## Abstract Epidemiological evidence suggests that intake of folate and other B‐vitamins and genetic variants in the one‐carbon metabolism pathway could influence the risk of breast cancer. Previous studies have focused on 2 polymorphisms in the methylenetetrahydrofolate gene (__MTHFR__ A222V and E