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Polymorphisms in CRHR1 and the serotonin transporter loci: Gene × Gene × Environment interactions on depressive symptoms

✍ Scribed by Kerry J. Ressler; Bekh Bradley; Kristina B. Mercer; Todd C. Deveau; Alicia K. Smith; Charles F. Gillespie; Charles B. Nemeroff; Joseph F. Cubells; Elisabeth B. Binder

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 354 KB
Volume: 9999B
Category: Article
ISSN: 1552-4841
DOI: 10.1002/ajmg.b.31052

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## Abstract Early institutional deprivation is a risk factor for Attention‐Deficit/Hyperactivity Disorder (ADHD) symptoms. However not all individuals are affected. We tested the hypothesis that this heterogeneity is influenced by gene x environment (GxE) interaction and that genetic polymorphisms