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Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease

✍ Scribed by T. HLAVATY; M. PIERIK; L. HENCKAERTS; M. FERRANTE; S. JOOSSENS; N. VAN SCHUERBEEK; M. NOMAN; P. RUTGEERTS; S. VERMEIRE

Book ID
108604243
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
161 KB
Volume
22
Category
Article
ISSN
0269-2813

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Predictive value of epithelial gene expr
Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease
✍ Ingrid Arijs; Roel Quintens; Leentje Van Lommel; Kristel Van Steen; Gert De Hert πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 432 KB

Background: Infliximab (IFX) has become the mainstay of therapy of refractory Crohn's disease (CD). However, a subset of patients shows incomplete or no response to this agent. In this study we investigated whether we could identify a mucosal gene panel to predict (non)response to IFX in CD. Method