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Polymorphisms and haplotypes of the HLA-class II and tumor necrosis factor region in multiple sclerosis patients and their parents

✍ Scribed by Marie-Paule, Roth; Nogueira, Leonor; Riond, Joëlle; Coppin, Hélène; Cambon-Thomsen, Anne; Clayton, John


Book ID
121902164
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
137 KB
Volume
36
Category
Article
ISSN
0198-8859

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✍ Ali H. Hajeer; Jane Worthington; Alan J. Silman; William E. R. Ollier 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 546 KB

Objective. To investigate 1) tumor necrosis Factor (TNF) microsatellite allele frequencies in rheumatoid arthritis (RA), and 2) associations between TNF microsatellites and RA-associated HLA specificities in order to build up extended HLA haplotypes. Methods. Eighty-five Caucasoid patients with RA