## Abstract Although elevation of blood and platelet serotonin has been documented in autism, genetic analyses of serotonin transporter gene have given conflicting results. Tryptophan 2,3 dioxygenase (TDO2) is the rateβlimiting enzyme in the catabolism of tryptophan, the precursor of serotonin. A m
β¦ LIBER β¦
Polymorphism ofFXR1 showing lack of association with autism
β Scribed by Limprasert, Pornprot; Zhong, Nan; Dobkin, Carl; Brown, W. Ted
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 10 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0148-7299
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## Abstract The TPH1 and TPH2 genes encode the rateβlimiting enzymes that control serotonin biosynthesis, and serotonin is clearly altered in autism. In the current study, eight SNPs in the TPH1 gene region and eight SNPs within the TPH2 gene were examined by familyβbased association tests in a lar