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Polymorphism of the cytokine genes and IgA nephropathy

✍ Scribed by Syrjänen, Jaana; Hurme, Mikko; Lehtimäki, Terho; Mustonen, Jukka; Pasternack, Amos

Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
84 KB
Volume
61
Category
Article
ISSN
0085-2538

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✍ Goto, Shin; Narita, Ichiei; Saito, Noriko; Watanabe, Yasuo; Yamazaki, Hajime; Sa 📂 Article 📅 2002 🏛 Nature Publishing Group 🌐 English ⚖ 91 KB

## Background: The m235t polymorphism of the angiotensinogen gene (agt) is associated with an increased risk of primary hypertension, which may then lead to progressive renal disease. recent studies showed that nucleotide substitution in the 5' upstream core promoter region of agt affects the basal