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Polymorphism of plasminogen in Tuscany (Italy)

✍ Scribed by I. Spinetti; R. Domenici; A. Giari; M. Bargagna

Book ID: 104664589
Publisher: Springer-Verlag
Year: 1990
Tongue: German
Weight: 399 KB
Volume: 103
Category: Article
ISSN: 0937-9827
DOI: 10.1007/bf00207338

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✦ Synopsis

The distribution of PLG phenotypes in the population of Tuscany (Central Italy) has been investigated by means of isoelectric focusing followed by immunofixation of desialyzed sera. In a random sample of 383 unrelated healthy blood donors registered at the Hospital of Pisa, three common phenotypes, PLG A, A-B, and B, and two rare variants were found. The allele frequencies calculated in our study were: PLG*A = 0.6749, PLG*B = 0.3225, and PLG*rare = 0.0026. The theoretical exclusion rate in cases of disputed paternity is 17.42%.

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